Search results for '' in Knowledge
We've found '41159' results.
ANTENNA AND RADIOWAVE PROPAGATION 6TH SEM complete
AWP complete notes 6th sem
MD ALI HASNAIN
Jee main 20o19 memory based answer
Where is the answers of JEE main 2019 question paper memory based
Soham Sengupta
COMPUTER NETWORK ASSIGNMENT
THERE IS A AVAILABLE FOR YOUR PROBLEM SOLUTION.
Mohit Jain
C Programming-Introduction to c and computer
In this ppt there are programs and detailed concepts related to c programming and examples regarding introduction.You can know how to use and use of c programming in a program.
Kilari Harshitha Naidu
चुनाव-2019, मतदान क्यों आवश्यक, चुनाव आयोग UPSC/UPPCS/ Other State PCS Mains & Essay Exams
Current Affairs Part-4 PDF ??? https://drive.google.com/file/d/1-Hnw9tfhe5svNzWpPhybZnZ7yMK7qxse/view?usp=drivesdk Current Affairs Part-3 PDF ??? https://drive.google.com/file/d/1NIa1x_K2rkYpo-IVHmz3bp1064oy49AI/view?usp=drivesdk Current Affairs Part-2 PDF ??? https://drive.google.com/file/d/1BvqRiJ0MOlc1Ojc7iIuD8W7l2qiiPzye/view?usp=drivesdk Current Affairs Part-1 PDF ??? https://drive.google.com/file/d/1qOePlRnDwPLZh_38qEmeDkCdjQhTcnAy/view?usp=drivesdk #VoteKar #UPSC #UPPCS #Essay पीसीएस-2018 मुख्य परीक्षा टेस्ट कार्यक्रम??? https://drive.google.com/file/d/1P-sBvCEE1JE1beLbokv8XWKKn_kty7zA/view?usp=drivesdk आरओ/एआरओ मुख्य परीक्षा टेस्ट कार्यक्रम??? https://drive.google.com/file/d/1J8F_oREx_nG7RPW6YKPyo-9jaZAqlWxs/view?usp=drivesdk पूरे नोट्स 30 निबंध की पूरी फ्रेमिंग, हिंदी पत्र लेखन ! राशि: 500 मात्र बैंक अकाउंट Dhananjay Singh Ac. No.20236943947 IFSC Code: SBIN0007627, SANT NIRANKARI COLONY New Delhi SBI भेजकर, स्क्रीनशॉट 8802913517 पर ह्वाट्सएप करें
Abhiyan Civil Services
The 3 Stages of Failure in Life and Work
One of the hardest things in life is to know when to keep going and when to move on.On the one hand, perseverance and grit are key to achieving success in any field. Anyone who masters their craft will face moments of doubt and somehow find the inner resolve to keep going. If you want to build a successful business or create a great marriage or learn a new skill then “sticking with it” is perhaps the most critical trait to possess.On the other hand, telling someone to never give up is terrible advice. Successful people give up all the time. If something is not working, smart people don’t repeat it endlessly. They revise. They adjust. They pivot. They quit. As the saying goes, “Insanity is doing the same thing over and over again and expecting different results.” Life requires both strategies. Sometimes you need to display unwavering confidence and double down on your efforts. Sometimes you need to abandon the things that aren’t working and try something new. The key question is: how do you know when to give up and when to stick with it?One way to answer this question is to use a framework I call the 3 Stages of Failure.The 3 Stages of FailureThis framework helps clarify things by breaking down challenges into three stages of failure:Stage 1 is a Failure of Tactics. These are HOW mistakes. They occur when you fail to build robust systems, forget to measure carefully, and get lazy with the details. A Failure of Tactics is a failure to execute on a good plan and a clear vision.Stage 2 is a Failure of Strategy. These are WHAT mistakes. They occur when you follow a strategy that fails to deliver the results you want. You can know why you do the things you do and you can know how to do the work, but still choose the wrong what to make it happen.Stage 3 is a Failure of Vision. These are WHY mistakes. They occur when you don't set a clear direction for yourself, follow a vision that doesn't fulfill you, or otherwise fail to understand why you do the things you do.In the rest of this article, I’ll share a story, solution, and summary for each stage of failure. My hope is that the 3 Stages of Failure framework will help you navigate the tricky decision of deciding when to quit and when to stick with it. It's not perfect, but I hope you find it to be useful.
harshit patel
Money and Banking
Money is regarded any object which is generally accepted as: medium of exchange, unit of account i.e. common measure of value, standard of deferred payment,store of value, transfer of value. A bank is a financial institution which deals with money, accepts deposits, advances loans, and create credits with the sole purpose of earning profits. Modern banks performs a wide variety of functions.
AKSHAT RAO PATIL
smokinhg
tdtydytdytuyfuyfi7g
swapan dev
sql-sqlite-commands-cheat-sheet(1)
sql-sqlite-commands-cheat-sheet(1)
A.C Classes
Non uniform flow
Non uniform flow
Sai Teja Gujja
Coco-Cola
Coca Cola and it's Macro - Micro environment and latest developments.
Kushagr Goyal
Protein Structure and Function
Proteins• Make up about 15% of the cell• Have many functions in the cell– Enzymes, Structural, Transport, Motor, Storage, Signaling, Receptors, Gene regulation, Special functionsShape = Amino Acid Sequence• Proteins are made of 20 amino acids linked by peptide bonds• Polypeptide backbone is the repeating sequence of the N-C-C-N-C-C… in the peptide bond• The side chain or R group is not part of the backbone or the peptide bondProtein Folding• The peptide bond allows for rotation around it and therefore the protein can fold and orient the R groups in favorable positions• Weak non-covalent interactions will hold the protein in its functional shape – these are weak and will take many to hold the shapeNon-covalent Bonds in ProteinsGlobular Proteins• The side chains will help determine the conformation in an aqueous solutionHydrogen Bonds in ProteinsH-bonds form between 1) atoms involved in the peptide bond; 2) peptide bond atoms and R groups; 3) R groupsProtein Folding• Proteins shape is determined by the sequence of the amino acids• The final shape is called the conformation and has the lowest free energy possible• Denaturation is the process of unfolding the protein– Can be down with heat, pH or chemical compounds– In the chemical compound, can remove and have the protein renature or refoldRefolding• Molecular chaperones are small proteins that help guide the folding and can help keep the new protein from associating with the wrong partnerProtein Folding• 2 regular folding patterns have been identified – formed between the bonds of the peptide backbone• a-helix – protein turns like a spiral – fibrous proteins (hair, nails, horns)• b-sheet – protein folds back on itself as in a ribbon –globular proteinb Sheets• Core of many proteins is the b sheet• Form rigid structures with the H-bond• Can be of 2 types: Anti-parallel – run in an opposite direction of its neighbor (A)– Parallel – run in the same direction with longer looping sections between them (B)a Helix• Formed by a H-bond between every 4th peptide bond – C=O to N-H• Usually in proteins that span a membrane• The a helix can either coil to the right or the left• Can also coil around each other – coiled-coil shape – a framework for structural proteins such as nails and skinLevels of Organization• Primary structure : Amino acid sequence of the protein• Secondary structure: H bonds in the peptide chain backbone• a-helix and b-sheets• Tertiary structure : Non-covalent interactions between the R groups within the protein• Quaternary structure: Interaction between 2 polypeptide chainsProtein StructureDomains• A domain is a basic structural unit of a protein structure – distinct from those that make up the conformations• Part of protein that can fold into a stable structure independently• Different domains can impart different functions to proteins• Proteins can have one to many domains depending on protein sizeUseful Proteins• There are thousands and thousands of different combinations of amino acids that can make up proteins and that would increase if each one had multiple shapes• Proteins usually have only one useful conformation because otherwise it would not be efficient use of the energy available to the system• Natural selection has eliminated proteins that do not perform a specific function in the cellProtein Families• Have similarities in amino acid sequence and 3-D structure• Have similar functions such as breakdown proteins but do it differentlyProteins – Multiple Peptides• Non-covalent bonds can form interactions between individual polypeptide chains– Binding site – where proteins interact with one another– Subunit – each polypeptide chain of large protein– Dimer – protein made of 2 subunits• Can be same subunit or different subunitsSingle Subunit ProteinsDifferent Subunit Proteins• Hemoglobin : 2 a globin subunits & 2 b globin subunitsProtein Assemblies• Proteins can form very large assemblies• Can form long chains if the protein has 2 binding sites – link together as a helix or a ring• Actin fibers in muscles and cytoskeleton – is made from thousands of actin molecules as a helical fiberTypes of Proteins• Globular Proteins – most of what we have dealt with so far– Compact shape like a ball with irregular surfaces– Enzymes are globular• Fibrous Proteins – usually span a long distance in the cell– 3-D structure is usually long and rod shapedImportant Fibrous Proteins• Intermediate filaments of the cytoskeleton – Structural scaffold inside the cell• Keratin in hair, horns and nails• Extracellular matrix – Bind cells together to make tissues– Secreted from cells and assemble in long fibers • Collagen – fiber with a glycine every third amino acid in the protein• Elastin – unstructured fibers that gives tissue an elastic characteristicCollagen and ElastinStabilizing Cross-Links• Cross linkages can be between 2 parts of a protein or between 2 subunits• Disulfide bonds (S-S) form between adjacent -SH groups on the amino acid cysteineProteins at Work• The conformation of a protein gives it a unique function• To work proteins must interact with other molecules, usually 1 or a few molecules from the thousands to 1 protein • Ligand – the molecule that a protein can bind• Binding site – part of the protein that interacts with the ligand– Consists of a cavity formed by a specific arrangement of amino acids
Hrithik Anand
Basic mechanical engineering: Boilers
This document consists of past year questions of Boilers of RTU end term examination.This will help students in making themselves familiar with the type of questions asked in university exam.
Ashutosh shukla
Moment distribution method
The moment distribution method is a structural analysis method for statically indeterminate beams and frames developed by Hardy Cross. It was published in 1930 in an ASCE journal.[1] The method only accounts for flexural effects and ignores axial and shear effects. From the 1930s until computers began to be widely used in the design and analysis of structures, the moment distribution method was the most widely practiced method.
AAYUSH LAL ROY
Mechanics-System of particles
In this pdf there are problems and detailed concepts related to engineering mechanics and regarding system of particles.You will be able to know how to use system of particles and solve the problems easily.